Safety and efficacy not established in pediatric patients. ![]() The safety and efficacy of an additional dose has not been established.There are 2 dosage regimens (low dose or high dose) to choose from.Indicated for patients treated with rivaroxaban and apixaban, when reversal of anticoagulation is needed because of life-threatening or uncontrolled bleeding. ![]() Injection, Lyophilized Powder for ReconstitutionÄosage Considerations – Should be Given as Follows:
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